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Symbol
Name
ID
Pparg
peroxisome proliferator activated receptor gamma
MGI:97747
Phenotype annotations related to liver/biliary system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Hepatic steatosis
Abnormality of the hepatic vasculature
Hepatosplenomegaly
Hepatomegaly
Cirrhosis
Extrahepatic cholestasis
Jaundice
Neoplasm of the liver
Disease(s) Associated with PPARG
familial partial lipodystrophy type 3
pancreatic cancer
pre-eclampsia

Mouse Phenotypes
liver/biliary system phenotype
enlarged liver
increased liver weight
increased liver triglyceride level
abnormal hepatocyte morphology
decreased susceptibility to diet-induced hepatic steatosis
hepatic steatosis
macrovesicular hepatic steatosis
microvesicular hepatic steatosis
pale liver
Availability Mouse Genotype
Ppargtm1Auw/Ppargtm1Auw
Ppargtm1Yec/Ppargtm1Yec *
Ppargtm1Avp/Pparg+
Ppargtm1Lja/Pparg+
Ppargtm1Tka/Pparg+
Ppargtm2(tTA)Yba/Pparg+
Ppargtm3(tTA)Yba/Pparg+
Ppargtm2Rev/Ppargtm2Rev
Tg(Fabp4-cre)1Rev/0  (conditional)
Ppargtm2Rev/Ppargtm2Rev
Tg(Tek-cre)1Ywa/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory